Keep Eyes on Integrins

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Keep Eyes on Integrins

In mammals, there are 18 kinds of α subunit and 8 kinds of β subunit were discovered, which form 24 combinations (Table 1) [2,3]. Overall, these 24 kinds of integrins can be divided to two groups by containing α-I domain (Table 1 and Figure 1A) or not (Table 1 and Figure 1B). Integrin can regulate its ligand-binding affinity by conformational changes [1]. The adaptor proteins and signal pathway...

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ژورنال

عنوان ژورنال: Journal of Immunobiology

سال: 2016

ISSN: 2476-1966

DOI: 10.4172/2476-1966.1000106